Carcinoma Intraepithelial (Panyakit Bowen) (Intraepithelial carcinoma (Bowen disease)) nembongkeun proliferasi sél skuamosa atipik sapanjang sakabéh ketebalan épidermis. Tumorna terbatas dina épidermis sareng henteu nyerang dermis. Panyakit ieu sacara téknis digolongkeun kana kanker, tapi henteu invasif, béda ti kanker umum (nyaéta kanker kalayan prognosis anu saé).
Biasana muncul salaku lesi erythematous, bersisik, atawa berkerak di mana waé dina awak. Lokasi anu paling umum nyaéta suku handap.
Éta tiasa diubaran ku sababaraha pilihan perawatan sapertos cryotherapy, curettage, cautery, terapi photodynamic, atanapi excision of lesion.
Squamous-cell skin cancer is one of the main types of skin cancer along with basal cell cancer, and melanoma. It usually presents as a hard lump with a scaly top but can also form an ulcer. Onset is often over months. Squamous-cell skin cancer is more likely to spread to distant areas than basal cell cancer. When confined to the outermost layer of the skin, a precancerous or in situ form of cSCC is known as Bowen's disease.
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Kasus ieu — Carcinoma Intraepithelial (Panyakit Bowen) (Intraepithelial carcinoma (Bowen disease)) bisa jadi misdiagnosis salaku eksim tahan lila, teu gatel.
Cutaneous horn — Teu kawas kutil, éta muncul salaku nodul keras, sarta biopsi diperlukeun pikeun mariksa aya henteu malignancy.
Lamun tatu tetep lila, kanker kulit kudu dianggap.
Carcinoma Intraepithelial (Panyakit Bowen) (Intraepithelial carcinoma (Bowen disease)) – Kasus ieu
Dina hal ieu, Irritated seborrheic keratosis ogé tiasa dianggap salaku diagnosis diferensial poténsial.
Ieu sering disalahpahaman salaku gangguan alérgi (contohna, nummular eczema).
Carcinoma Intraepithelial (Panyakit Bowen) (Intraepithelial carcinoma (Bowen disease)) ― Kasus ieu
Kasus séjén nunjukkeun fitur morfologis anu sarupa jeung kaayaan alérgi.
Bowen's disease (BD) nyaéta jinis kanker kulit anu dimimitian dina lapisan luar kulit (épidermis). Éta langkung umum di Kaukasia sareng sering kajantenan di daérah anu kakeunaan sinar panonpoé, tapi ogé tiasa muncul di tempat sanés. BD biasana muncul salaku lesi tunggal. BD mindeng ditempo salaku tanda peringatan saméméh tipe anu leuwih serius tina kanker kulit tumuwuh. Pikeun nangtukeun jinis panyakitna, dokter biasana ngandelkeun pamariksaan sampel jaringan dina mikroskop (biopsy). Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease lolobana mangaruhan jalma bodas umur leuwih ti 60. Faktor résiko konci ngawengku paparan panonpoé jangka panjang, sistem imun lemah, paparan arsén, sarta inféksi HPV dina kulit. Galur HPV 16, 18, 34, jeung 48 numbu ka kasakit Bowen di wewengkon séks. Keterlibatan HPV dina kasus non-génital kurang jelas. Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Biasana muncul salaku lesi erythematous, bersisik, atawa berkerak di mana waé dina awak. Lokasi anu paling umum nyaéta suku handap.
Éta tiasa diubaran ku sababaraha pilihan perawatan sapertos cryotherapy, curettage, cautery, terapi photodynamic, atanapi excision of lesion.
○ Diagnosis sareng Perawatan
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy