Intraepithelial carcinoma (Bowen disease) - Carcinoma Intraepithelial (Panyakit Bowen)
☆ Dina hasil Stiftung Warentest 2022 ti Jerman, kapuasan konsumen sareng ModelDerm ngan ukur langkung handap tibatan konsultasi telemedicine anu mayar.
Kasus has ― Carcinoma Intraepithelial (Panyakit Bowen) (Intraepithelial carcinoma (Bowen disease)) bisa jadi misdiagnosis salaku éksim tahan lila, non-itchy.
References
Bowen's disease (BD) nyaéta jenis kanker kulit anu dimimitian dina lapisan luar kulit (épidermis) . Éta langkung umum di Kaukasia sareng sering kajantenan di daérah anu kakeunaan sinar panonpoé, tapi ogé tiasa muncul di tempat sanés. BD biasana muncul salaku lesi tunggal. BD mindeng ditempo salaku tanda peringatan saméméh tipe leuwih serius kanker kulit tumuwuh. Pikeun nangtukeun jenis panyakitna BD, dokter biasana ngandelkeun examining sampel jaringan dina mikroskop (biopsy) .
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease lolobana mangaruhan jalma bodas umur leuwih 60. Faktor résiko konci kaasup paparan panonpoé jangka panjang, sistim imun lemah, paparan arsén, sarta inféksi HPV kulit. Galur HPV 16, 18, 34, jeung 48 numbu ka kasakit Bowen di wewengkon séks. Keterlibatan HPV dina kasus non-génital kurang jelas.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Biasana muncul salaku erythematous, scaly atanapi crusty wewengkon mana dina awak. Lokasi anu paling umum nyaéta suku handap.
Éta tiasa diubaran ku sababaraha pilihan perawatan sapertos cryotherapy, curettage, cautery, terapi photodynamic, atanapi excision of lesion.
○ Diagnosis sareng Perawatan
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy